Educational Articles

Dogs + Medications & Supplements

  • Paroxetine is given by mouth and is used off label to treat certain behavior disorders such as aggression, anxiety, and urine-marking. Give as directed by your veterinarian. Common side effects include sleepiness and decreased appetite. Do not use in pets that are allergic to it or other SSRIs, or pets currently taking MAOIs. If a negative reaction occurs, please call your veterinary office.

  • Penicillin G (brand names VetriPen G, PenOne Pro, others), is an antibiotic used to treat susceptible infections in cats, dogs, chickens, horses, livestock, ferrets, hedgehogs, rabbits, and other animals. It is used off label (extra label) in cats, dogs, and other companion animals. Penicillin G comes in injectable suspension form. Caution when using in rabbits and other animals sensitive to penicillin-like drugs.

  • Pentoxifylline is given by mouth and is used off label to treat skin disorders and poor perfusion due to inflamed blood vessels. Give as directed. Common side effects include vomiting, diarrhea, lack of appetite, excitement, or restlessness. Do not use in pets that are allergic to it, allergic to xanthines, or in pets with bleeding in the brain or eye. If a negative reaction occurs, please call your veterinary office.

  • Perna is given by mouth and is used over the counter to treat inflammatory conditions such as arthritis in cats, dogs, and horses. Give as directed by your veterinarian. The most common side effects are gastrointestinal effects such as nausea and diarrhea. Do not use in pets that are allergic to it or other shellfish, or in pregnant or nursing pets. If a negative reaction occurs, please call your veterinary office.

  • Phenobarbital is given by mouth or as an injection to treat seizures or to sedate your pet. Common side effects include sleepiness, increased thirst, urination, and/or appetite. Do not use this medication in pets with liver, lung, or kidney disease or those that are allergic to barbiturates. If a negative reaction occurs, call your veterinary office.

  • Phenoxybenzamine is given by mouth and is used off label to treat urination difficulty related to sphincter tone, high blood pressure related to pheochromocytoma, and laminitis in horses. Phenoxybenzamine should be given as directed by your veterinarian. Common side effects include nausea, vomiting, diarrhea, small pupils, increased heart rate, and nasal congestion/stuffy nose. Do not use in pets that are allergic to it, in pets that cannot handle low blood pressure, or in horses with colic. If a negative reaction occurs, please call your veterinary office.

  • Phenylpropanolamine is given by mouth and is used on and off label to treat urinary incontinence. Give as directed by your veterinarian. The most common side effects include vomiting, diarrhea, lack of appetite, increased thirst, restlessness, irritability, and difficulty urinating. Do not use in pets that are allergic to it or are pregnant. If a negative reaction occurs, please call your veterinary office.

  • Pheromones (brand names Feliway®, Comfort Zone®, Adaptil®, others) are natural or synthetic substances that mimic scents released by animals to communicate. Pheromones are used in cats and dogs as behavior modifiers for a variety of conditions, including urine spraying and marking, inter-cat aggression, stressful events, phobias, and separation anxiety, among other conditions. Pheromones comes in collar, diffuser, and spray forms.

  • Phytonadione (brand names: Mephyton®, Phytomenadione®, Aqua-Mephyton®, K-Caps®, Konakion®, Hemophyt®) is given by mouth and is used on and off label to treat vitamin K1 deficiencies in a variety of animal species, usually due to toxicities. Give as directed by your veterinarian. Side effects are uncommon. Do not use in pets that are allergic to it unless the benefits outweigh the risks. If a negative reaction occurs, please call your veterinary office.

  • Phytosphingosine topical (brand names Douxo®, SkinGuard®) is an anti-inflammatory agent, with antibacterial and antifungal properties. It is used in cats and dogs to help relieve itching in certain skin conditions and help restore the skin barrier. Phytosphingosine topical may be part of a combination product.

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